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In recent years, Ozempic (semaglutide) has gained widespread attention—not just for its role in managing Type 2 diabetes, but also for its weight loss benefits. With rising interest across India, especially in urban centres like Hyderabad, many individuals are exploring this medication as a possible solution for sustained weight management.
At Clinica Derm, we understand that body confidence is an essential part of overall well-being. Under the expert guidance of Dr. Deepthi Atmakuri, we take a holistic and patient-centred approach—blending modern medicine with non-invasive aesthetic treatments for safe, sustainable fat reduction.
What Is Ozempic?
Ozempic is the brand name for semaglutide, a prescription drug first approved in 2017 by the FDA to treat type 2 diabetes. It belongs to a class of medications known as GLP-1 receptor agonists. These drugs help manage blood sugar levels by increasing insulin production and decreasing sugar release from the liver. One added effect: they slow digestion, helping people feel fuller longer—resulting in weight loss.
While Ozempic wasn’t created for weight loss, the active ingredient, semaglutide, is also used in another drug called Wegovy, which is FDA-approved for managing obesity.
Why Are People Using Ozempic for Weight Loss?
The answer lies in its effectiveness. In clinical studies, people taking higher doses of semaglutide for weight loss (as in Wegovy) experienced an average of 15% body weight loss in just over a year. That’s a significant result compared to other weight-loss methods, especially for those struggling with obesity.
Because Ozempic and Wegovy contain the same ingredient (though in different doses), some healthcare providers prescribe Ozempic “off-label” to treat obesity—especially when Wegovy is in short supply or unaffordable.
But here’s the catch: Ozempic is not FDA-approved for weight loss—and its rising off-label use has caused a ripple effect.
How Does It Help with Weight Loss?
Semaglutide promotes weight loss through several mechanisms:
- Appetite suppression: Makes you feel full longer by slowing down gastric emptying.
- Improved insulin function: Regulates blood sugar and reduces fat storage.
- Reduced cravings: Helps limit snacking and overeating.
These effects have been validated in clinical trials like the STEP program, where participants saw up to 15% body weight reduction over the course of one year, especially when paired with healthy lifestyle changes.
Who Should and Shouldn’t Take Ozempic?
Ozempic may be recommended for individuals who:
- Are overweight or obese (BMI > 27 with comorbidities or >30)
- Struggle with long-term weight management despite diet and exercise
- Are under close medical supervision
However, it is not suitable for everyone. Those with a history of thyroid cancer, pancreatitis, or certain gastrointestinal disorders should avoid it. Pregnant or breastfeeding women should also not use this medication.
Why It’s Not a “Quick Fix”
A common misconception is that you can take Ozempic for a few months, lose the weight, and then stop. In reality, weight often returns when the medication is discontinued—especially if no lifestyle changes were made during the process.
This is because of something called your “weight set point”—a range your body defends. When you diet, your body tries to hold onto weight by slowing your metabolism and increasing hunger hormones. Medications like Ozempic may help lower that set point, but long-term use is usually required for long-term results.
That’s why Ozempic isn’t a shortcut. It’s part of a comprehensive plan that includes changes in diet, exercise, and behaviour. Think of it like treating blood pressure or cholesterol—it’s not a crash diet; it’s medical care for a chronic condition.
Limitations of Ozempic Alone
Despite the results, medications like Ozempic have certain limitations:
- Cannot target specific fat pockets, such as the abdomen or thighs
- Weight regain is possible once the medication is stopped
- May require long-term use for sustained benefits
- Some individuals experience persistent or bothersome side effects
Is Ozempic Right for You?
If you are living with obesity or have a BMI over 30 (or 27 with related health conditions), medications like Ozempic may be appropriate—but only under a doctor’s guidance. Just as not everyone with elevated cholesterol is prescribed statins, not everyone looking to lose a few pounds should turn to Ozempic.
It’s also essential to look beyond the scale. Better health, improved mobility, fewer hospital visits, and lower long-term risks for heart and kidney disease matter more than the number on your jeans.
Final Thoughts
While Ozempic has shown impressive potential for weight loss, it’s not a one-size-fits-all solution. For those looking for safe, non-surgical, and more aesthetic-focused fat loss options, Clinica Derm offers cutting-edge treatments suitable for your needs.
Whether you’re interested in semaglutide or exploring non-invasive sculpting techniques, we’re here to guide you every step of the way.
Book a consultation with Dr. Deepthi Atmakuri at Clinica Derm, Hyderabad, to discover the best approach to your weight loss journey—inside and out.